System Reference Document

RANGED COMBAT

From the turn of the 20th century onwards, civilized persons have primarily used ranged weapons like firearms to kill and maim one another. Characters Attack in ranged combat by making an Attack Roll using the appropriate Combat Skill (Pistols, Automatics, Rifles, Throwing Weapons, or Heavy Weapons). Roll 2d6 and add the appropriate Skill Bonus; if the result is greater than or equal to the target's modified Defense, your Attack hits and deals damage. 

Based ranged combat damage is determined entirely by the weapon used, with the exception of non-explosivethrowing weapons, which add Strength-based bonus damage just like one-handed melee weapons

Several factors make ranged combat slightly more complicated to resolve than melee combat.